Expression of GLUT2 in insulin-secreting AtT20 pituitary cells

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Expression of GLUT2 in insulin-secreting AtT20 pituitary cells.

The importance of the glucose transporter isoform, GLUT2, in the construction of glucose-sensitive surrogate insulin-secreting cells was evaluated using murine pituitary AtT20 cells. The cells were double transfected with cDNAs for human preproinsulin (hppI-1) driven by the cytomegalovirus promoter, and human GLUT2 driven by the beta-actin promoter. The stably transfected clone, AtTinsGLUT2.36,...

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ژورنال

عنوان ژورنال: Journal of Molecular Endocrinology

سال: 1998

ISSN: 0952-5041,1479-6813

DOI: 10.1677/jme.0.0200075